| City | Population |
| Eunice, NM | 2,922 |
| Jal, NM | 2,047 |
| Ackerly, TX | 220 |
| Alpine, TX | 5,905 |
| Andrews, TX | 11,088 |
| Andrews County rural, TX | 2,883 |
| Balmorhea, TX | 479 |
| Barstow, TX | 349 |
| Big Spring, TX | 27,282 |
| Borden County rural, TX | 410 |
| Brewster County rural, TX | 2,606 |
| Coahoma town, TX | 817 |
| Coyanosa, TX | 163 |
| Crane, TX | 3,353 |
| Crane County rural, TX | 1,022 |
| Dawson County rural, TX | 4,170 |
| Denver City town, TX | 4,479 |
| Ector County rural, TX | 12,652 |
| Forsan, TX | 210 |
| Fort Davis, TX | 1,201 |
| Fort Stockton, TX | 8,283 |
| Gail, TX | 231 |
| Gaines County rural, TX | 8,454 |
| Garden City, TX | 334 |
| Gardendale, TX | 1,574 |
| Glasscock County rural, TX | 892 |
| Goldsmith, TX | 257 |
| Grandfalls town, TX | 360 |
| Howard County rural, TX | 5,868 |
| Imperial, TX | 278 |
| Iraan, TX | 1,229 |
| Jeff Davis County rural, TX | 1,007 |
| Kermit, TX | 5,708 |
| Lamesa, TX | 9,422 |
| Lindsay, TX | 271 |
| Loop, TX | 225 |
| Los Ybanez, TX | 19 |
| Loving County rural, TX | 63 |
| Marathon, TX | 430 |
| Marfa, TX | 1,981 |
| Martin County rural, TX | 2,087 |
| McCamey, TX | 1,887 |
| McKinney Acres, TX | 815 |
| Mentone, TX | 19 |
| Midland, TX | 111,147 |
| Midland County rural, TX | 25,725 |
| Monahans, TX | 6,953 |
| Odessa, TX | 99,940 |
| Pecos, TX | 8,780 |
| Pecos County rural, TX | 5,554 |
| Presidio, TX | 4,426 |
| Presidio County rural, TX | 1,321 |
| Pyote town, TX | 114 |
| Rankin, TX | 778 |
| Redford, TX | 90 |
| Reeves County rural, TX | 4,163 |
| Sand Springs, TX | 835 |
| Seagraves, TX | 2,417 |
| Seminole, TX | 6,430 |
| Stanton, TX | 2,492 |
| Study Butte, TX | 233 |
| Terlingua, TX | 58 |
| Thorntonville town, TX | 476 |
| Toyah town, TX | 90 |
| Upton County rural, TX | 690 |
| Valentine town, TX | 134 |
| Ward County rural, TX | 2,370 |
| West Odessa, TX | 22,707 |
| Wickett town, TX | 498 |
| Wink, TX | 940 |
| | |
| Total | 445,313 |
